🧬 Researcher Preview · macOS · Free during beta

The plasmid editor
your bench deserves.

PlasmoD is a modern molecular biology workbench — circular and linear map views, full-featured sequence editing, Gibson / Golden Gate / CRISPR cloning design, and multiple sequence alignment. Fully offline. No subscription. No SnapGene.

Request Early Access See what's inside →

macOS 12+ · Apple Silicon & Intel · No account needed

Used in early preview by researchers at Cambridge · ETH Zürich · MIT · Oxford

Everything you need at the bench.

Built by a molecular biologist who was tired of SnapGene's price tag.

Circular & Linear Maps

Interactive plasmid map with feature arcs, tooltips, and click-to-select. Linear overview with resizable panels and GC% track.

Sequence Editor

Full sequence view with feature colouring, live selection stats, six-frame translation, and keyboard-driven editing.

Cloning Workspace

Gibson Assembly, Golden Gate, and CRISPR design. Automatic primer design, homology check, and assembled-product preview.

Multiple Sequence Alignment

Align up to 20 sequences (ClustalW-style) with consensus track, conservation colouring, and pairwise identity matrix.

Sequence Library

Save, tag, and search your own sequence collection. Import entire lab plasmid inventories from GenBank files.

Fully Offline

No cloud, no account, no telemetry. Your sequences stay on your machine. NCBI search is optional and never required.

Every format your lab uses.

Import from any source, export to any destination.

Import & Export
  • GenBank .gb / .gbk
  • FASTA .fasta / .fa
  • EMBL .embl
  • SnapGene .dna
  • Plain DNA text
Import only
  • Paste raw sequence (FASTA / plain)
  • Drag & drop any file onto the window
  • NCBI accession number search

Get early access.

PlasmoD is in researcher preview. Enter your name and email below — your personalised license file and the correct DMG for your Mac will arrive within seconds. No payment, no account.

  • ✓ 90-day beta license
  • ✓ Both Apple Silicon and Intel builds available
  • ✓ Direct reply-to-email support
  • ✓ Your feedback shapes the next version

→ Apple menu → About This Mac → look for "Apple M…" or "Intel Core"

By submitting you agree to receive one email with the download files. No marketing, no newsletter. Your data is only used to generate your personal license.

Common questions.

Is PlasmoD free?

During the beta, yes — completely free. You get a 90-day license. When the public version launches there will be a paid tier, but beta participants will receive a discount.

Do I need to be online to use it?

No. PlasmoD runs entirely offline after installation. The only optional network feature is the NCBI sequence search, which you can ignore entirely.

macOS says "unidentified developer" — is it safe?

This is a Gatekeeper warning because PlasmoD is a researcher preview and not yet Apple-notarised. To open it: System Settings → Privacy & Security → "PlasmoD was blocked" → Open Anyway. You only need to do this once.

Can I use my license on multiple Macs?

Each license binds to the first Mac it activates on. If you need to transfer to a new machine, email support@plasmod.com and we will reset it within one business day.

What happens when my 90-day license expires?

PlasmoD will show an expiry screen and stop working. Email us to request a renewal — we will issue a new 90-day license immediately, no questions asked during the beta period.

Is my sequence data private?

Completely. PlasmoD never transmits your sequences anywhere. The only outbound requests are the optional NCBI search (which you initiate explicitly) and the one-time license activation at this website when you first request access.

Does it work on Windows or Linux?

Not yet. The beta is macOS-only (12 Monterey or later). Windows and Linux builds are planned for the 1.0 public release.